family-ownded since 1975
We are your competent partner for high-quality medical products and dental preparations.
Since the company was founded in 1975, our family-ownded company has been the reliable partner for dentists in Germany and abroad.
Our expertise and many years of experience guarantee you consistently high quality from the raw material to the product, of course certified according to DIN EN 13485 and with the "Made in Germany" label.
Why us?
Since the company was founded in 1975, our family-ownded company has been the reliable partner for dentists in Germany and abroad.
Handmade
Our products are made in-house
and assembled.
No automated technology.
Made in Germany
From raw material to finished product,
everything is "Made in Germany".
DIN EN 13485 Certified
Our expertise and many years of experience
guarantee you consistently high quality from the raw material to the
product
Family and owner managed since 1975
The focus of our daily work
is quality and service orientation
for our customers
Competent advice
direct advice whether by mail, phone or chat.
You always speak to the right contact person
Our focus for you
Click through our focal points in the field of tooth preservation
and learn always a little more.

A radiant smile with healthy teeth - for a lifetime with our Tiefenfluorid ®. For children but also adults additionally with fruity-sweet taste as
Tiefenffluorid ® junior.
In the case of incipient paro pH-balancing and germ-reducing with Tiefenfluorid® balance.
Optimal preparation of the cavity or the crown die is half the battle for an excellent result.
In addition to removing grease, moisture and residues of resin fillings with our
cavity washing liquid, this also includes protecting the pulp to prevent sensitivities by using the
Dentin-Versiegelungsliquid - Dentin sealing liquid.
In the case of metal fillings or crowns, it is possible to seal with
Kavitätenspalt-Dichtungsmixtur - Cavity-fissure sealing-mixture can be used to seal the marginal gaps and firmly anchor the filling.
Everything for dental preservation is more than just a motto for us. Therefore we offer with our
Calciumhydroxid-hochdispers -
Calcium hydroxide-highly dispersed and
Cupral
®
two effective products for antibiotic-free root canal treatment. Ready-mixed and ready for immediate use.
For the irrigation of canals you have with our
Cupral
® liquid is an effective aid.
You can effectively stop bleeding with our
Hämostatikum Al-Cu - Haemostatic agent.
Our alkaline cements
Atacamite-Wurzelfüllzement - root filling cement and
Inetrims-Kronenzement - Iterim crown cement slowly set to form calcium hydroxide.
The resulting alkaline environment stops initial inflammatory stimuli.
Both have low strength and are therefore easily removable.
No implant is as good as the natural tooth.
The
Depotphorese® is our holistic method for root canal treatment in which a weak electric field is used to
Cupral
®
is transported through all large, small and even curved canals to the apex. Can also be used for fragmented instruments in the root canal and root canals that cannot be completely prepared.
Also available as "Depotphorese
® to go" with our
Galvanisches Stirfelement - galvanic pin elements.
Cupral
®
- Your antibiotic-free alternative to chlorhexidine.
With a powerful effect and without affecting the taste.
For flushing pockets and channels, you have the perfect solution with our Cupral ® liquid you have an effective helper.
Our
Hämostatikum Al-Cu - Haemostatic agent acts quickly and reliably.
It can be rinsed off without reopening the bleeding.
In addition, it has a germ-reducing effect and can of course be used with most impression materials without interaction.
Portfolio
Our products are all "Made in Germany" from our manufactory.
Of course you can find all our products in our
shop.
Our team
Your contact persons can be reached directly at
+49518124633
Mondays to Fridays from 08:00 to 16:30

Dr. Constanze Knappwost-Gieseke
Managing Director

Dr. Katja Günther-Schade
Quality management

Benedict Henne
Sales

Lutz Jordan
Engineering

Sabrina Stopka-Marhauer
Marketing

Ursel Knappwost
Senior-
Managing Director
Our timeline
When did what happen at Humanchemie?

- November 2020
45th anniversary
45th anniversary
November 1, 2020Due to Corona, this unfortunately could not be celebrated! - May 2017
Product launch Cupral® - liquid
Product launch Cupral® - liquid
May 1, 2017Presentation of the Cupral® - liquid at the IDS in Cologne - May 2015
40th anniversary
40th anniversary
May 1, 2015 - May 2013
Product launch of the "MAGIS" Depotphorese device
Product launch of the "MAGIS" Depotphorese device
May 31, 2013Introduction of the Depotphorese® instrument "MAGIS" incl. Apex measurement at the 18th BASS Congress in Skopje Presentation of the results of a study on the treatment treatment of cervical hypersensitivities with deep fluoridation from the working group around Dr. Agron Meto (University of Tirana) - January 2008
1st Depotphoresis - User Meeting
1st Depotphoresis - User Meeting
January 1, 2008First Depotphorese user meeting in Weimar. - January 2006
Certification according to DIN EN ISO 13485:2003
Certification according to DIN EN ISO 13485:2003
January 1, 2006Certification according to DIN EN ISO 13485:2003 and EC Directive 93/42 EWG Annex II - January 2006
Dr. C. Knappwost-Gieseke becomes Managing Director
Dr. C. Knappwost-Gieseke becomes Managing Director
January 1, 2006In addition to Ursel Knappwost, Dr. Constanze Knappwost-Gieseke is now also appointed Managing Director - January 2003
Certification according to DIN EN ISO 13488:2001
Certification according to DIN EN ISO 13488:2001
January 1, 2003Certification according to DIN EN ISO 13488:2001 and EC Directive 93/42 EWG Annex II - January 2000
Optimization Atacamit-Wurzelfüllzement - Root filling cement
Optimization Atacamit-Wurzelfüllzement - Root filling cement
January 1, 2000Optimization of the atacamite root canal filling cement (medium strength, good X-ray contrast) - January 1999
Product Launch Single Hand Dosing Syringes
Product Launch Single Hand Dosing Syringes
January 1, 1999Cupral and calcium hydroxide are also available in the single-handed dosing syringe available - January 1997
Certification according to DIN EN ISO 9002
Certification according to DIN EN ISO 9002
January 1, 1997Certification according to DIN EN ISO 9002/ DIN EN 46002 and EC Directive 93/42 EEG Annex II - November 1975
Company foundation
Company foundation
November 6, 1975Company founded under the management of Ursel Knappwost and Heinrich Röhrkasten. 14 different products for tooth preservation (e.g. enamel sealing liquid, today Tiefenfluorid, and copper-calcium hydroxide, today Cupral). All products are developed by Univ.-Prof. Dr. Dr. h. c. med. dent. A. Knappwost (Universities of Tübingen and Hamburg). See also under the photo.